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| Saturday, September 1st , 2046 |
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| RP Jason Griffin retired from professional baseball. |
| RP Craig Williams retired from professional baseball. |
| RP David Soto retired from professional baseball. |
| CF Alex Torres retired from professional baseball. |
| SP Javier Sierra retired from professional baseball. |
| C Richard Lapham retired from professional baseball. |
| C Brian Russell retired from professional baseball. |
| C Ricky Armenta retired from professional baseball. |
| RP Matt Landis retired from professional baseball. |
| C Tony Perez retired from professional baseball. |
| Friday, June 22nd , 2046 |
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| Drafted SP Andrew Purkis in the 2046 first-year player draft (Round 1, Pick 2, 2nd overall pick). |
| Drafted C Alex Ortiz in the 2046 first-year player draft (Round 5, Pick 2, 98th overall pick). |
| Drafted C Lyndon Callaghan in the 2046 first-year player draft (Round 6, Pick 2, 121st overall pick). |
| Drafted 3B Fernando Alcantara in the 2046 first-year player draft (Round 7, Pick 2, 145th overall pick). |
| Drafted SP Rob Reiff in the 2046 first-year player draft (Round 8, Pick 2, 168th overall pick). |
| Drafted SP Dillon Jones in the 2046 first-year player draft (Round 9, Pick 2, 192nd overall pick). |
| Drafted SP Brendan Youngblood in the 2046 first-year player draft (Round 10, Pick 2, 216th overall pick). |
| Sunday, May 13th , 2046 |
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| Placed SS Johnny Soto on the reserve roster. |
| Placed CF Jason Miraglia on the reserve roster. |
| Placed SS Rob Stepheson on the active roster. |
| Placed CF David Loubier on the active roster. |
| Placed RP Marquis Moore on the reserve roster. |
| Placed SP Derek Beaner on the active roster. |
| Thursday, March 29th , 2046 |
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| Placed CL Jonathan Keyes on the reserve roster. |
| Placed RF Chris Allen on the reserve roster. |
| Placed C Angel Pino on the reserve roster. |
| Placed RF Dan Rankin on the reserve roster. |
| Placed 2B Howard Woodruff on the reserve roster. |
| Placed 2B Logan Carpenter on the reserve roster. |
| Placed 1B Brian Carrington on the reserve roster. |
| Placed RP Max Graham on the reserve roster. |
| Placed LF Justin Kline on the reserve roster. |
| Placed RP Marquis Moore on the reserve roster. |
| Placed SP Brian Tuttle on the reserve roster. |
| Placed SP Christian Brownie on the reserve roster. |
| Placed SP Gus Gonzales on the reserve roster. |
| Placed C Chris Hahn on the reserve roster. |
| Placed SP Daniel Rodriguez on the reserve roster. |
| Placed SP Javier Sierra on the reserve roster. |
| Placed SP German Ledezma on the reserve roster. |
| Placed SP Mark Herrera on the reserve roster. |
| Placed CF Justin Burleson on the reserve roster. |
| Placed SP Mike DeMonte on the reserve roster. |
| Placed SP Joseph Duran on the reserve roster. |
| Placed SP Richard Estrada on the reserve roster. |
| Placed 1B Mike Hadd on the reserve roster. |
| Placed SS Byron Rivers on the reserve roster. |
| Placed SP Mauricio Alameda on the active roster. |
| Placed SP Ramon Salinas on the active roster. |
| Placed SP Matt McGrail on the active roster. |
| Placed RP Max Graham on the active roster. |
| Placed SP Daniel Rodriguez on the active roster. |
| Placed CL Kerry Poss on the active roster. |
| Placed RP Marquis Moore on the active roster. |
| Placed SP Brian Tuttle on the active roster. |
| Placed RP Jonathan Briseno on the active roster. |
| Placed SP Rich Aguilar on the active roster. |
| Placed SP Mark Herrera on the active roster. |
| Placed RP Jeff Hocutt on the active roster. |
| Placed CL Jonathan Keyes on the active roster. |
| Placed C Dave Guzman on the active roster. |
| Placed RF Chris Allen on the active roster. |
| Placed 2B Matt Blasdell on the active roster. |
| Placed 3B Antonio Torres on the active roster. |
| Placed SS Johnny Soto on the active roster. |
| Placed CF Hector Reyes on the active roster. |
| Placed RF Sergio Alonso on the active roster. |
| Placed RF Hugo Martinez on the active roster. |
| Placed RF Jeff Taylor on the active roster. |
| Placed C Lon Munson on the active roster. |
| Placed RF Dan Rankin on the active roster. |
| Placed 2B Josh Carranza on the active roster. |
| Placed CF Jason Miraglia on the active roster. |
